Rh-Negative Patients

by Rachel Simmons May 28, 2021 Updated: December 29, 2021

An Indirect Coombs test is used to determine if a pregnant patient is Rh-positive or Rh-negative.

An Indirect Coombs test is used to determine if a pregnant patient is Rh-positive or Rh-negative.

Rh-negative patients will receive Rh Immune Globulin (RhoGAM):

  • At ~26 - 28 weeks gestation.
  • After giving birth to a Rh-positive baby (within 72 hrs).

RhoGAM prevents formation of antibodies (i.e. Rh sensitization) that can cause hemolytic disease during future pregnancies.



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