AFP measurement

by Cathy Parkes April 19, 2021 Updated: December 29, 2021

Alpha-fetoprotein (AFP) levels are measured with prenatal bloodwork or with an amniocentesis.  HIGH levels of AFP are associated with neural tube defects. LOW levels of AFP are associated with chromosomal disorders (such as Down Syndrome).

Alpha-fetoprotein (AFP) levels are measured with prenatal bloodwork or with an amniocentesis. These tests are usually performed at 15-20 weeks gestation.

HIGH levels of AFP are associated with neural tube defects.

LOW levels of AFP are associated with chromosomal disorders (such as Down Syndrome).

Low = ↓ down.Low AFP levels = risk for down syndrome.



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