What's the difference between Pharm Basics and Pharmacology?
The Pharmacology Basics video series, and our Pharmacology Basics and Safe Medication Administration Flashcards for Nursing Students will teach you about medications, pharmacokinetics, prescriptions, routes of administration, and the key facts and concepts you need to know to build a strong foundation to excel in Pharmacology on the ATI, HESI or NCLEX.
This series won't cover specific medications. If you have established your baseline education in Pharmacology and are ready to move on to learning specific medications, check out our Nursing Pharmacology series and our Pharmacology Flashcards for Nursing Students.
Drug Names
Drugs have a chemical name, a generic name, and a brand name.
Chemical name
The chemical name of a drug conveys the exact chemical constitution of a medication including the placement of atoms. If you had to take an organic chemistry class as a prerequisite for nursing school, then you may be familiar with these types of names.
The good news is, as a nursing student and a practicing nurse, you do not have to know chemical names.
For example, N-acetyl-p-aminophenol is the chemical name for acetaminophen.
Generic name
The generic name of a drug can be used by any country or manufacturer, and the first letter of that drug name is not capitalized because it is not a proper noun.
When studying, we encourage you to focus on the generic names of medications because when you're taking a test, the generic name of a medication will always be given. However, you will not always be given the brand name. If you learn a brand name and not the generic name, and then that generic name shows up on a test, you're going to be out of luck. So make sure that you learn the generic names.
For example, acetaminophen is the generic name for Tylenol.
Brand name
The use of a brand name of a drug is restricted to only that manufacturer of that drug, and it is capitalized as a proper noun.
For example, Tylenol is just one brand name under which acetaminophen is sold.
Pharmacology - Nursing Flashcards
Medication Regulation
In the United States, medication is regulated by the federal government, primarily the Food and Drug Administration (FDA), who also works with other federal agencies, like the Drug Enforcement Administration (DEA) and Department of Health and Human Services (HHS).
For the purposes of Pharmacology Basics, the key medication regulations you need to know about are the US Drug Schedule and the Drug Risk Classification for Pregnancy.
US Drug Schedule
The US Drug Schedule was put forth by the Controlled Substances Act (CSA), a federal statute. This act created five schedules (classifications or categories) for drugs depending on their potential for abuse, currently accepted medical use, safety and potential for addiction.
What are the different US drug schedules?
The CSA defines five different schedules of controlled substances, numbered I-V.
- Schedule I
- Schedule II
- Schedule III
- Schedule IV
- Schedule V
Schedule I drugs have the highest potential for abuse and include illegal drugs like heroin or LSD (acid).
Schedule V drugs have a lower risk of abuse, but still a potential for abuse. Some examples of Category V medications include cough medicines with codeine, and pregabalin (Lyrica).
What is a scheduled drug?
If a drug falls into Schedule I, II, III, IV, or V as defined by the CSA, it is considered "a scheduled drug."
Are all drugs scheduled?
No. It's important to note that these categorizations are not used for all possible drugs (e.g., aspirin). The US Drug Schedules are used only for the drugs that are considered controlled substances because they meet the criteria outlined for Schedules I-V as defined by the CSA.
How are the US drug schedules defined?
The CSA defines the different drug schedules based on these questions:
- How likely is the drug to be abused?
- Is this drug used as a treatment by medical providers in the US?
- Is this drug safe? How likely is the drug to cause addiction? And if it will, what kinds of addiction?
Based on the answers to these questions, the drug is grouped into Schedule I, Schedule II, III, IV, or V.
What you need to know about scheduled drugs for nursing
Regulations surrounding scheduled drugs may vary across states, but in general, telephone orders are not acceptable. The provider must write and sign the order for scheduled drugs.
Also, no prescription refills are allowed on scheduled drugs, and if a patient needs more of one of these medications, they will need to go visit the provider first, who will write a new prescription.
Drug Risk Classification in Pregnancy
Drug risk classification in pregnancy is the FDA's system for classifying how safe a medication is for the mother and baby during pregnancy. These classifications come in A, B, C, D, and X.
Category A is the safest during pregnancy, and Category X is the most dangerous during pregnancy.
As a general matter, when in doubt, assume all medications are not safe during pregnancy unless otherwise noted by the provider.
Medication Reconciliation
Medication reconciliation is the process of compiling a complete and updated list of all of the medications that your patient is taking, including over-the-counter medications and herbal supplements. This list should be compared to (reconciled against) the provider's orders. This important process helps maintain consistency with the patient's medications and evaluate potential interactions between their prescribed medications, their herbal supplements, and what the provider has ordered.
Herb-Drug interaction
There are some key herbal supplements that are known to cause interactions with prescribed medications. These supplements to watch out for include garlic, ginger, ginkgo biloba, St. John's wort, valerian, and saw palmetto.
Garlic, Ginger, Ginkgo Biloba
Garlic, Ginger, and Ginkgo Biloba increase a patient's bleeding risk if they are also taking aspirin, NSAIDs, and warfarin.
St. John’s Wort
St. John’s Wort increases the risk of serotonin syndrome if a patient is also taking serotonin reuptake inhibitors (SSRIs) like fluoxetine or sertraline. St. John’s Wort also decreases effectiveness of oral contraceptives, anticoagulants, and digoxin.
These medications, including their side effects and administration tips are covered in our Pharmacology Flashcards for Nursing Students.
Valerian
Valerian (often sold as valerian root extract) increases sedation with CNS depressants like benzodiazepines.
Saw Palmetto
Saw palmetto increases bleeding risk and interferes with hormonal therapies like testosterone and oral contraceptives.